The Human Body (PY4010)

Provide accurate account of the following: 1. Describe the environmental factors that lead to the development of cancer 2. Describe the abnormalities of cell signalling in cancer cells 3. Describe the biological events of cancer metastasis

Describe the working of a cholinergic nerve terminal and the receptors upon it, including any feedback mechanisms.

Explain how competitive, non-competitive and allosteric enzyme inhibition mechanisms work.

The parasympathetic nervous system is the part of the autonomic nervous system that stimulates the body’s “rest and digest” processes. Assuming that you have just had a heavy meal, describe SIX responses that might be stimulated by the parasympathetic nervous system.

Outline the key events that result in an arrest in the cell cycle in a p53 competent cell following DNA damage.

List ONE paracrine and FOUR endocrine secretions of the alimentary tract and their functions.