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26 Post - Post Lab 26
Post Lab 26
Course
Biochemistry/Lab (CHEM 3650)
163 Documents
Students shared 163 documents in this course
University
Nova Southeastern University
Academic year: 2022/2023
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Nova Southeastern University
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Payal Kalia June 9, 2022
a.
b. The metabolic advantage of having liver PK activated by fructose-1,6-bisphosphate Is that the liver pyruvate kinase can produce pyruvate quickly when there is a high concentration of the fructose-1,6-bisphosphate. Therefore, the liver can produce glucose whenever needed in the body. c. If the liver responded hyperbolically to PEP, gluconeogenesis would be affected. This is because it would cause the process to continue without a stop. It would cause a production of glucose constantly even when not needed in the body.
Payal Kalia June 9, 2022
- Oxaloacetate formation from pyruvate is catalyzed by pyruvate carboxylase. Therefore, the carboxyl group that is formed in the oxaloacetate at the fourth carbon position has the radioactive carbon 14 label. When the oxaloacetate is broken down, the carbon dioxide that is released contains the carbon 14 label as well. The PEP molecule has the carbon 14 label as well which is then transferred to the glucose in its third and fourth carbon.
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26 Post - Post Lab 26
Course: Biochemistry/Lab (CHEM 3650)
163 Documents
Students shared 163 documents in this course
University: Nova Southeastern University
Was this document helpful?
Payal Kalia June 9, 2022
a.
b. The metabolic advantage of having liver PK activated by fructose-1,6-bisphosphate Is that
the liver pyruvate kinase can produce pyruvate quickly when there is a high concentration
of the fructose-1,6-bisphosphate. Therefore, the liver can produce glucose whenever
needed in the body.
c. If the liver responded hyperbolically to PEP, gluconeogenesis would be affected. This is
because it would cause the process to continue without a stop. It would cause a
production of glucose constantly even when not needed in the body.
