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Pharmacodynamics and therapeutics lecture

Pharmacodynamics and therapeutics lecture notes
Course

Pharmacokinetics and Medication Administration (NURS 205)

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Pharmacodynamics and

therapeutics

Nurs 205

● The study of what the drug does to the body

● The mechanism of drug actions in living tissues

● Therapeutic effect

Pharmacodynamics

Copyright © 2020 Elsevier Inc. All

Rights Reserved. 0

1

Pharmacotherapeutics

● The desired therapeutic outcome should be:

● Individualized

● Collaborative

- specific to patient's problem

- discussing to get maxi um effect

for patient's problem /all healthcare team members)

Outcome goals

● Preventing a disease or unwanted condition

● Ex -

● Improving the quality of life

● Ex. -

Vaccines

managing their symptoms

Critical thinking question

● What is the difference between a

contraindication and an adverse effect?

Contradiction

Adverse

rm -

• situation where we did not • Action/response to drug

administer the drug b/c aware after we

gave

the

of drug

something like liver disease

Adverse Effect

● Any undesirable effects that are a direct

response to one or more drugs.

Types of Therapy (Page #27)

● Acute

● Maintenance

● Supplemental

-0A

intense treatment for a short period of time

type of therapy taken on a

daily everyday to take

drug

everyday to maintain condition

replacementofasubstanuneededmm

for maintaining normal function

ex : different types of vitamins

we take to maintain normal

*insulin is functioning

considered a supplement

bk Our bodies produce it but others

not may

Patient Monitoring

● Therapeutic index- ratio of a drug’s toxic level

to the level that provides therapeutic benefit

● Drug concentration – in blood

● Patient condition – concurrent disease or

other medical condition (infection, GI

function, Cardiovascular function etc.)

take blood to

determine cone to see

if they reached therapeutic level

● Tolerance: decreasing response to repeated drug

doses

● Dependence: physiologic or psychological need

for a drug

● Physical dependence: physiologic need for a drug

to avoid physical withdrawal symptoms

● Psychological dependence: also known as

addiction and is the obsessive desire for the

euphoric effects of a drug

Patient monitoring

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ex : 1mg of morphine for patient for 6 mnths ; may have to up dose to get same affect

ex : 1mg of morphine 1 year; body gets used to- it /patient will have withdraw 1 symptoms

Interactions

● Alteration of the action of one drug by

another drug or food.

● Antagonistic – combination of 2 drugs results

in drug effects that are less than the sum of the

effects for each drug given separately ( 1+ 1=

???)

● Incompatibilities – for parenteral drugs.

1+1 = 12

2 drugs

1+1=7 2 will be reacting if

we administer @ same

time.

if can't mix

drug : 1st and thenmed then flush

administer

next drug

● Other drug effects

● Teratogenic – causes structural defect in fetus

● Mutagenic- causes permanent change in genetic

composition

● Carcinogenic effects- cancer causing effect

Pharmacotherapeutics (Cont.)

Copyright © 2020 Elsevier Inc. All

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Pharmacodynamics and therapeutics lecture

Course: Pharmacokinetics and Medication Administration (NURS 205)

73 Documents
Students shared 73 documents in this course

University: Widener University

Was this document helpful?
Pharmacodynamics and
therapeutics
Nurs 205