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Basics of bioinformatics
Bioinformatics (BIF514)
Amrita Vishwa Vidyapeetham
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Bioinformatics
Bioinformatics is the application of computer technology to the field of biology and medicine. It is used in drug designing and drug development. Bioinformatics has become one of the fastest growing fields, which will certainly reveal the mysteries of life and will bring cure for many diseases.
Bioinformatics is been an inevitable part of Biotechnology in the current era.
Bioinformatics is the use of computers, software tools, and databases to handle biological information
Bioinformatics is the comprehensive application of mathematics, statistics, biochemistry, biophysics and computer algorithms to analyze biological data. Bioinformatics is the creation of data algorithms and specialized computer software to identify and classify components of a biological system, such as DNA and protein sequences. Bioinformatics is a science straddling the domains of biomedical, informatics, mathematics and statistics.
Bioinformatics is applying computational techniques to biology data. Bioinformatics is a combination of molecular biology and computer sciences.
Bioinformatics is the use of computational approach to analyse, manage and store biological data. Bioinformatics has become very important in the field of Biotechnology.
All the information process by Biotechnology is stored and analyzed using Bioinformatics.
Bioinformatics impacts on all aspects of biological research. An emerging interdisciplinary research area. The term Bioinformatics was first published in 1991.
Bioinformatics only made possible for completing the Human Genome Project.
It is the shortened form of “Biological Information”
Need for Bioinformatics
The number of entries in databases of gene sequences is increasing exponentially. Bioinformaticians are needed to understand and use this information.
Genome sequencing projects, including human genome project are producing vast amounts of information. The challenge is to use this information in a useful way. The huge amount of sequence information available cannot be analyzed manually. Computers have become essential tools in the study of information. This was predicted by Watter Gilbers who won a Nobel prize for his contribution to the discovery of DNA sequencing. He emphasized the focus of molecular biology must shift towards computer-assisted biological sequence analysis. The application of computational techniques to solve biological problems.
Application of information technology to the storage, management and analysis of biological information Bioinformatics is the unified discipline formed from the combination of biology, computer science, and information technology. “The mathematical, statistical and computing methods that aim to solve biological problems using DNA and amino acid sequences and related information”. The branch of science concerned with information and information flow in biological systems, esp. the use of computational methods in genetics and genomics. The marriage between computer science and molecular biology
The algorithm and techniques of computer science are being used to solve the problems faced by molecular biologists ‘Information technology applied to the management and analysis of biological data’ Storage and Analysis are two of the important functions – bioinformaticians build tools for each
Proteomics data analysis Protein Evolution
Other uses: Drug designing Vaccine development
Dairy technology Forensics
Crop improvement Designing enzymes for detergents Genetic counseling
Recent events making bioinformatics more important
Exponential expansion of biological information Expansion of multiple types of information
Cheaper high throughput technologies Improvement in computation power Lack of standards/quality
Need for micro and macro analysis Need for better algorithms As the definition suggests there are two parts involved in it namely the biology part and the computer part. The Biology part can be discussed under three subheadings: Genomics
Proteomics and Drug Designing
Basics of bioinformatics
Course: Bioinformatics (BIF514)
University: Amrita Vishwa Vidyapeetham
