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Muscular System
Course: Nursing (RLE70)
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Students shared 769 documents in this course
University: Capitol University
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Muscular System
Graded responses
• Graded responses are different degrees of skeletal muscle
shortening
• Muscle fiber contraction is “all-or-none,” meaning the muscle
fiber (not the whole muscle) will contract to its fullest extent when
stimulated adequately
• Within a whole skeletal muscle, not all fibers may be stimulated
during the same interval
• Different combinations of muscle fiber contractions may give
differing responses
• Graded responses can be produced in two ways
• By changing the frequency of muscle stimulation
• By changing the number of muscle cells being stimulated a
tone time
Muscle response to increasingly rapid stimulation
• Muscle twitch
• Single, brief, jerky contraction
• Not a normal muscle function
• In most types of muscle activity, nerve impulses are
delivered at a rapid rate
• As a result, contractions are “summed” (added) together, and
one contraction is immediately followed by another
• When stimulations become more frequent, muscle
contractions get stronger and smoother
• The muscle now exhibits unfused (incomplete) tetanus
• Fused (complete) tetanus is achieved when the muscle is
stimulated so rapidly that no evidence of relaxation is seen
• Contractions are smooth and sustained
Muscle response to stronger stimuli
• Muscle force depends upon the number of fibers stimulated
• Contraction of more fibers results in greater muscle tension
• When all motor units are active and stimulated, the muscle
contraction is as strong as it can get
Providing Energy for Muscle Contraction
• ATP
• Only energy source that can be used to directly power
muscle contraction
• Stored in muscle fibers in small amounts that are quickly
used up
• After this initial time, other pathways must be utilized to
produce ATP
• Three pathways to regenerate ATP
1. Direct phosphorylation of ADP by creatine phosphate
2. Aerobic pathway
3. Anaerobic glycolysis and lactic acid formation
• Direct phosphorylation of ADP by creatine phosphate (CP)
—fastest
• Muscle cells store CP, a high-energy molecule
• After ATP is depleted, ADP remains
• CP transfers a phosphate group to ADP to regenerate ATP
• CP supplies are exhausted in less than 15 seconds
• 1 ATP is produced per CP molecule
• Aerobic respiration
• Supplies ATP at rest and during light/moderate exercise
• A series of metabolic pathways, called oxidative
phosphorylation, use oxygen and occur in the mitochondria
• Glucose is broken down to carbon dioxide and water, releasing
energy (about 32 ATP)
• Slower reaction; requires continuous delivery of oxygen and
nutrients
• Anaerobic glycolysis and lactic acid formation
•Reaction that breaks down glucose without oxygen
• Glucose is broken down to pyruvic acid to produce about 2
ATP
• Pyruvic acid is converted to lactic acid
Muscle Fatigue and Oxygen Deficit
• If muscle activity is strenuous and prolonged, muscle fatigue
occurs
• Suspected factors that contribute to muscle fatigue include:
• Ion imbalances (Ca+2 and K+)
• Oxygen deficit and lactic acid accumulation
• Decrease in energy (ATP) supply
• After exercise, the oxygen deficit is repaid by rapid, deep
breathing
Types of Muscle Contractions
• Isotonic contractions
• Myofilaments are able to slide past each other during
contractions
• The muscle shortens, and movement occurs
• Example: bending the knee; lifting weights, smiling
• Isometric contractions
• Muscle filaments are trying to slide, but the muscle is pitted
against an immovable object
• Tension increases, but muscles do not shorten
• Example: pushing your palms together in front of you
• Muscle tone
• State of continuous partial contractions
• Result of different motor units being stimulated in a systematic
way
• Muscle remains firm, healthy, and constantly ready for action