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Integumentary System summary
Course: BS Nursing (BSN)
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Laurena Escondo, 2018
INTEGUMENTARY SYSTEM
General functions:
1. Protection
2. Sensation
3. Temperature
4. Vitamin D production
5. Excretion
SKIN
Epidermis
- superficial layer, consists of epithelial tissue.
- Resists abrasion and reduces water loss.
-
Stratified squamous epithelial.
- No blood vessels (avascular)
TYPES of CELLS composing EPIDERMIS
§ Keratinocytes
§ Melanocytes
§ Merkel Cells
§ Langerhans
Keratinization- when keratinocyte stemcells undergoes mitosis, new cell forms and pushes older cells to the
skin surface.
REGIONS of EPIDERMIS (5 strata/s)
1. Stratum Basale
(malphigian layer)
- Single layer cuboidal/columnar cells.
Ø Hemidesmosomes
o Provides structural strength
o Anchor to basement membrane
Ø Desmosomes
o Holds keratinocytes
- Keratinocyte undergoes mitotic division for 19 days.
- It takes 45-56 days for a cell to reach the epidermal surface.
- Stem cells give rise in this layer.
- Site of melanin formation.
2. Stratum Spinosum
- Pre-keratin site.
- Superficial to basale.
- Consists of 8-10 layers of many sided cells.
- Membrane bound organelles are produced in this layer (inside the keratinocytes)—
Lamellar bodies.
3. Stratum Granulosum
- Keratin site.
- Consists of 2-5 layers of cells.
- Named from the presence of keratohyalin.
4. Stratum Lucidum
- Consists of several layers of dead skin cells.
- “clear layer”
- Has Eleiden—a soft gel-like structure to resist water.