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Drug Study - Olanzapine, Divalproex sodium

Olanzapine, Divalproex sodium
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Science technology

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Students shared 44 documents in this course
Academic year: 2022/2023
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Drug

Name

Classification Mechanism of

Action

Indication Contraindication Adverse

Reaction

Nursing Responsibilities

Generic

Name:

Olanzapine

Brand

Name:

Lybalvi,

Olazax,

Symbyax,

Zalasta,

Zypadhera

, Zyprexa

Actual

dosage,

route,

frequency

:

Adult -

1 tab, 10

mg, qhs

PO

Atypical

Antipsychotic

The effect of

olanzapine in

the D2 receptor

is reported to

produce the

positive effects

of this drug

such as a

decrease in

hallucinations,

delusions,

disorganized

speech,

disorganized

thought, and

disorganized

behavior. On

the other hand,

its effect on the

serotonin

5HT2A receptor

prevents the

onset of

anhedonia, flat

affect, alogia,

avolition and

poor attention.

Treatment

of Acute

agitation,

Delirium

Management

of Bipolar 1

disorder,

Schizophrenia

Contraindicated

with allergy to

olanzapine,

myeloproliferativ

e disorders,

severe CNS

depression,

comatose states,

lactation.

Use cautiously in

elderly or

debilitated

patients, or with

CV or

cerebrovascular

disease,

dehydration,

seizure disorders,

Alzheimer's

disease, prostate

enlargement,

narrow-angle

glaucoma,

history of

paralytic ileus or

breast cancer,

pregnancy.

CNS:

Somnolence,

dizziness,

nervousness,

headache,

akathisia,

personality

disorders, tardive

dyskinesia,

neuroleptic

malignant

syndrome

CV: Orthostatic

hypotension,

peripheral edema,

tachycardia

GI: Constipation,

abdominal pain

Respiratory:

Cough,

pharyngitis

Other: Fever,

weight gain, joint

pain, development

of diabetes

mellitus

Before:

Assess for: allergy,

contraindications.

Obtain: baseline VS, weight,

labs, ECG, bowel sounds,

CBC, urinalysis, liver and

renal function tests

During:

Monitor elderly patients for

dehydration and institute

remedial measures promptly;

· Encourage patient to void

before taking the drug

· Monitor for elevations of

temperature and differentiate

between infection and

neuroleptic malignant

syndrome.

· Monitor for orthostatic

hypotension and provide

appropriate safety measures

as needed.

After:

Monitor for signs of adverse

reactions.

Perform health teaching.

Was this document helpful?

Drug Study - Olanzapine, Divalproex sodium

Course: Science technology

44 Documents
Students shared 44 documents in this course
Was this document helpful?
Drug
Name
Classification
Mechanism of
Action
Indication
Contraindication
Adverse
Reaction
Nursing Responsibilities
Generic
Name:
Olanzapine
Brand
Name:
Lybalvi,
Olazax,
Symbyax,
Zalasta,
Zypadhera
, Zyprexa
Actual
dosage,
route,
frequency
:
Adult -
1 tab, 10
mg, qhs
PO
Atypical
Antipsychotic
The effect of
olanzapine in
the D2 receptor
is reported to
produce the
positive effects
of this drug
such as a
decrease in
hallucinations,
delusions,
disorganized
speech,
disorganized
thought, and
disorganized
behavior. On
the other hand,
its effect on the
serotonin
5HT2A receptor
prevents the
onset of
anhedonia, flat
affect, alogia,
avolition and
poor attention.
Treatment
of Acute
agitation,
Delirium
Management
of Bipolar 1
disorder,
Schizophrenia
Contraindicated
with allergy to
olanzapine,
myeloproliferativ
e disorders,
severe CNS
depression,
comatose states,
lactation.
Use cautiously in
elderly or
debilitated
patients, or with
CV or
cerebrovascular
disease,
dehydration,
seizure disorders,
Alzheimer's
disease, prostate
enlargement,
narrow-angle
glaucoma,
history of
paralytic ileus or
breast cancer,
pregnancy.
CNS:
Somnolence,
dizziness,
nervousness,
headache,
akathisia,
personality
disorders, tardive
dyskinesia,
neuroleptic
malignant
syndrome
CV: Orthostatic
hypotension,
peripheral edema,
tachycardia
GI: Constipation,
abdominal pain
Respiratory:
Cough,
pharyngitis
Other: Fever,
weight gain, joint
pain, development
of diabetes
mellitus
Before:
Assess for: allergy,
contraindications.
Obtain: baseline VS, weight,
labs, ECG, bowel sounds,
CBC, urinalysis, liver and
renal function tests
During:
Monitor elderly patients for
dehydration and institute
remedial measures promptly;
· Encourage patient to void
before taking the drug
· Monitor for elevations of
temperature and differentiate
between infection and
neuroleptic malignant
syndrome.
· Monitor for orthostatic
hypotension and provide
appropriate safety measures
as needed.
After:
Monitor for signs of adverse
reactions.
Perform health teaching.